Cytodiagnosis of metastatic amelanotic melanomas to the lymph node by fine needle aspiration cytology: adjunctival value of immunohistochemical staining and electron microscopy
نویسندگان
چکیده
Malignant melanoma is known for its wide range of histologic patterns and its ability to mimic other malignant tumors. Malignant melanoma is generated in the skin and sinus paranasalis by a malignant tumor of melanocytic origin. Malignant melanoma is usually quickly diagnosed by the presence of melanin granules. On the other hand, amelanotic melanoma is without melanin granules and is often difficult to differentiate from nonepithelial malignant tumors. Recently, fine-needle aspiration cytology (FNAC) was used to treat widespersed mammary glands, thyroid area, and lymph nodes. As for the reports of amelanotic melanomas that metastasize to the mammary gland and the ovary. However, no other detailed study has been reported on transmission electron microscopy. This study stresses the importance of immunohistochemical staining and electron microscopy for a Journal of Analytical Bio-Science Vol. 32, No 4 (2009)
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